| DNase {stats} | R Documentation |
The DNase data frame has 176 rows and 3 columns of data
obtained during development of an ELISA assay for the recombinant
protein DNase in rat serum.
data(DNase)
This data frame contains the following columns:
10 < ... < 3
indicating the assay run.
Davidian, M. and Giltinan, D. M. (1995) Nonlinear Models for Repeated Measurement Data, Chapman & Hall (section 5.2.4, p. 134)
Pinheiro, J. C. and Bates, D. M. (2000) Mixed-effects Models in S and S-PLUS, Springer.
data(DNase)
coplot(density ~ conc | Run, data = DNase,
show = FALSE, type = "b")
coplot(density ~ log(conc) | Run, data = DNase,
show = FALSE, type = "b")
## fit a representative run
fm1 <- nls(density ~ SSlogis( log(conc), Asym, xmid, scal ),
data = DNase, subset = Run == 1)
## compare with a four-parameter logistic
fm2 <- nls(density ~ SSfpl( log(conc), A, B, xmid, scal ),
data = DNase, subset = Run == 1)
summary(fm2)
anova(fm1, fm2)